US Patents and Published
Patent Applications


 
Publications List

The following is a list of publications/posters co-authored by Brian D. Gildea

Kuhn, Heiko; Demidov, Vadim V.; Coull, James M.; Fiandaca, Mark J.; Gildea, Brian D.; Frank-Kamenetskii,Maxim D. Hybridization of DNA and PNA Molecular Beacons to Single-stranded and Double-stranded DNA Targets. Journal of the American Chemical Society (2002), 124(6): 1097-1103.

Kuhn, Heiko; Demidov, Vadim V.; Gildea, Brian D.; Fiandaca, Mark J.; Coull, James M.; Frank-Kamenetskii, Maxim D. PNA Beacons for Duplex DNA. Antisense & Nucleic Acid Drug Development (2001), 11(4): 265-270.

Fiandaca, Mark J. ; Hyldig-Nielsen, Jens J.; Gildea, Brian D.; Coull, James M. Self-reporting PNA/DNA Primers for PCR Analysis. Genome Research (2001), 11(4): 609-613.

Gildea, Brian D.; Casey, Shelagh; MacNeill, Joan; Perry-O'Keefe, Heather; Sorensen, Ditte; Coull, James M.PNA Solubility Enhancers. Tetrahedron Letters (1998), 39(40): 7255-7258.

Christensen, Leif; Fitzpatrick, Richard; Gildea, Brian; Petersen, Kenneth H.; Hansen, Henrik F.; Koch, Troels; Egholm, Michael; Buchardt, Ole; Nielsen, Peter E. Solid-phase Synthesis of Peptide Nucleic Acids. Journal of Peptide Science (1995), 1(3): 185-83.

Christensen, Leif; Fitzpatrick, Richard; Gildea, Brian; Warren, Bill; Coull, James M. Improved Synthesis, Purification and Characterization of PNA Oligomers. Innovation Perspect. Solid Phase Synth. Collect. Pep., Int. Symp., 3rd (1994) , Meeting Date 1993, 149-56.

Koster, H.; Beck, S.; Coull, J. M.; Dunne, T.; Gildea, B. D.; Kissinger, C.; O'Keeffe, T. Oligonucleotide Synthesis and Multiplex DNA Sequencing Using Chemiluminescent Detection. Nucleic Acids Symposium Series (1991), 24 (Synth. Oligonucleotides: Probl. Front. Pract. Appl.), 318-21.

Nordlund, T. M.; Wu, P.; Andersson, S.; Nilsson, L.; Rigler, R.; Graeslund, A.; McLaughlin, L. W.; Gildea , B.Structural Dynamics of DNA Sensed by Fluorescence from Chemically Modified Bases. Proceedings of SPIE-The International Society for Optical Engineering (1990), 1204 (Time-Resolved Laser Spectrosc. Biochem. 2, Pt.1), 344-53.

Gildea, Brian D.; Coull, James M.; Koster, Hubert. A Versatile Acid-labile Linker for Modification of Synthetic Biomolecules. Tetrahedron Letters (1990), 31(49): 7095-8.

locono, Joseph A.; Gildea, Brian; McLaughlin, Larry W. Mild Acid Hydrolysis of 2-pyrimidinone-containing DNA Fragments Generates Apurinic/apyrimidinic Sites. Tetrahedron Letters (1990), 31(2): 175-8.

Gildea, Brian; McLaughlin, Larry W. The Synthesis of 2-pyrimidinone Nucleosides and Their Incorporation into Oligodeoxynucleotides. Nucleic Acids Research (1989), 17(6): 2261-81.